Dasantafil Raw Material CAS 569351-91-3
Dasentafil is a small molecule phosphodiesterase type 5 (PDE5) inhibitor primarily used as a research-stage compound for the treatment of erectile dysfunction (ED) and genitourinary system disorders.
ChemicalName: 7-[(3-bromo-4-methoxyphenyl)methyl]-1-ethyl-3,7-dihydro-8-[[(1R,2R)-2-hydroxycyclopentyl]amino]-3-(2-hydroxyethyl)-1H-purine-2,6-dione.
Dasantafil is mainly used to treat kidney yang deficiency, essence and blood deficiency, impotence and spermatorrhea, uterine cold syndrome and infertility, thinness, fatigue, chills, dizziness, tinnitus, deafness, cold pain in the waist and spine, muscle and bone weakness, metrorrhagia and metrostaxis, and deep-seated ulcers (yin-type abscesses).
Usage and Dosage: Take orally, 1-2 g, ground into powder and taken orally; or used in pills and powders.
Precautions
2.This product should be avoided by individuals with Yin deficiency and Yang excess, blood heat, intense stomach fire, lung phlegm-heat, or those suffering from external heat-related illnesses.
3.Avoid cold raw fruits and vegetables; refrain from consuming foods and drinks rich in monoamines, such as cheese, yogurt, animal liver, pickled fish, sausages, cured meats, broad beans, lentils, chocolate, yeast, fermented tofu, canned figs, pineapple, beer, wine, citrus juices, etc. Otherwise, excessive absorption of tyramine may cause a sudden spike in blood pressure.
4.Should not be used with alkaloids such as quinine, atropine, and ephedrine hydrochloride, as they may form precipitates and reduce drug absorption.
5.Should not be used with cardiac glycosides, as it may lead to cardiac glycoside toxicity.
6.Should not be used concurrently with potassium-losing diuretics (such as ethacrynic acid, furosemide, and acetazolamide), as it may cause hypokalemia.
7.Should not be used with hypoglycemic drugs that can raise blood sugar levels, potentially reducing the efficacy of hypoglycemic medications.
8.Should not be used with aspirin, sodium salicylate, etc., as it can induce or exacerbate gastrointestinal ulcers.
9.Should not be used with monoamine oxidase inhibitors.
10.Should not be used with chloral hydrate, as it can produce antagonistic effects
| Molecular weight | 522.39 |
| Molecular formula | C22H28BrN5O5 |
| CAS |
569351-91-3 |
| Appearance | White powder |
| Purity |
99% |
| Detection Method | High Performance Liquid Chromatography |
| Standard |
USP |
This product has a sex hormone-like effect and also has functions such as regulating bone metabolism, anti-fatigue, and enhancing immunity.
Related Discussions
1. Shennong Bencao Jing states: "It mainly deals with the discharge of evil blood,..." Boost energy and strengthen will, keeping one's teeth young."
2. "Mingyi Bielu" : "It is used to treat debility, vomiting like malaria, emaciation, soreness and pain in the limbs, pain in the waist and spine, frequent urination, and spermatorrhea with blood."
3. "Ben Jing Feng Yuan" states: "The function of deer antler is specifically for treating injuries in the middle, exhaustion, low back pain, and emaciation. It is suitable for tonifying fire and assisting Yang, generating essence and marrow, strengthening muscles and bones, consolidating essence and promoting defecation. It is also applicable to people with weak lower body, dizziness, and dark eyes." "
4. Compendium of Materia Medica: "It generates essence and replenishes marrow, nourishes blood and benefits Yang, and strengthens muscles and bones." It is used to treat all kinds of deficiency and damage, such as deafness, dim vision, dizziness and dysentery. For treating impotence and frequent urination, you can make deer antler wine by soaking yam in it and taking it.
5. It is used to treat exhaustion of essence and blood, sallow complexion, deafness, blurred vision, etc. It is combined with Angelica sinensis and Prunus mume paste to form pills (Jisheng Formula).
6. It is used to treat various deficiencies and damages, five kinds of fatigue and seven kinds of injuries, insufficiency of vital energy, cold intolerance and cold limbs, impotence and premature ejaculation, cold uterus and infertility, frequent urination and other conditions. It is often used in combination with ginseng, astragalus and Angelica, such as Shenrong Guben Pills (from the "Great Dictionary of Chinese Medicine").
7. For treating the later stage of fractures with poor healing, it is used in combination with Drynaria fortunei, Drynaria fortunei, and natural copper, etc.
8. It is used to treat continuous metrorrhagia and menorrhagia, weakness and emaciation. It is used in combination with cuttlefish bone, dragon bone, and sliced cuttlefish, such as Deer Antler Powder (from "Zhengzhi Zhunsheng").
9. For treating excessive leucorrhea, dog spine and Ampelopsis japonica can be combined, such as Ampelopsis japonica pills (Jisheng Formula).
10. For treating chronic ulcers and sores that do not heal, as well as internal abscesses and sores that do not recur, it is often combined with Angelica sinensis, Cinnamomum cassia, etc., such as Yanghe Decoction (Comprehensive Collection of Surgical Life).
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